Leesburg may refer to several locations in the United States of America:
- Leesburg, Alabama
- Leesburg, Florida
- Leesburg, Georgia
- Leesburg, Idaho, a community and historic district listed on the NRHP in Lemhi County, Idaho
- Leesburg, Illinois
- Leesburg, Indiana
- Leesburg, Kentucky
- Leesburg, Mississippi
- Leesburg, New Jersey
- Leesburg, Ohio
- Leesburg, Texas
- Leesburg, Virginia