Legionellales

Legionellales
Legionella sp. under ultraviolet illumination
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Legionellales
Families and genera

Legionellaceae
   Legionella
Coxiellaceae
   Aquicella
   Coxiella
   Diplorickettsia
   Rickettsiella
   "Ca. Berkiella"[1]
   "Ca. Fiscibacter"[1]
   "Ca. Ovatusbacter"[1]
   "Ca. Pokemonas"[1]

The Legionellales are an order of Pseudomonadota ("Proteobacteria"). Like all Pseudomonadota, they are Gram-negative.[2] They comprise two families, typified by Legionella and Coxiella, both of which include notable pathogens. For example, Q fever is caused by Coxiella burnetii and Legionella pneumophila causes Legionnaires' disease[3][4] and Pontiac fever.[5][6][7]

Members of the order Legionellales can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotein-releasing system transmembrane protein lolE and tRNA (guanosine(37)-N1)-methyltransferase TrmD.[8]

  1. ^ a b c d Marcel Dominik Solbach, Michael Bonkowski and Kenneth Dumack (2021): Novel Endosymbionts in Rhizarian Amoebae Imply Universal Infection of Unrelated Free-Living Amoebae by Legionellales. In: Front. Cell. Infect. Microbiol., 8 March 2021, doi:10.3389/fcimb.2021.642216. Along with:
    'Pokemonas': Bacteria related to lung parasites discovered, named after Pokémon. On: EurekAlert! 30-Apr-2021.
  2. ^ George M. Garrity: Bergey's Manual of Systematic Bacteriology. 2. Auflage. Springer, New York, 2005, Volume 2: The Proteobacteria, Part B: The Gammaproteobacteria
  3. ^ Fraser, D.W., Tsai, T,. Orenstein, W., et al. (1977). Legionnaires' disease: description of an epidemic of pneumonia. New England Journal of Medicine. 297:1189–1197.
  4. ^ McDade, JE., Shepard, C.C., Fraser, D.W., et al., (1977) Legionnaires' Disease — Isolation of a Bacterium and Demonstration of Its Role in Other Respiratory Disease. New England Journal of Medicine. 297: 1197–1203.
  5. ^ "General Information- Pontiac Fever". HPA. Retrieved 2013-04-07.
  6. ^ [1][dead link‍]
  7. ^ Fields, Barry S.; Haupt, Thomas; Davis, Jeffrey P.; Arduino, Matthew J.; Miller, Phyllis H.; Butler, Jay C. (2001). "Pontiac Fever Due to Legionella micdadei from a Whirlpool Spa: Possible Role of Bacterial Endotoxin". The Journal of Infectious Diseases. 184 (10). Jid.oxfordjournals.org: 1289–1292. doi:10.1086/324211. PMID 11679917.
  8. ^ Saini, Navneet; Gupta, Radhey S. (July 2021). "A robust phylogenetic framework for members of the order Legionellales and its main genera (Legionella, Aquicella, Coxiella and Rickettsiella) based on phylogenomic analyses and identification of molecular markers demarcating different clades". Antonie van Leeuwenhoek. 114 (7): 957–982. doi:10.1007/s10482-021-01569-9. ISSN 0003-6072. PMID 33881638. S2CID 233326323.