Leukemia cutis

Leukemia cutis
SpecialtyDermatology

Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions.[1] This condition may be contrasted with leukemids, which are skin lesions that occur with leukemia, but which are not related to leukemic cell infiltration.[1][2] Leukemia cutis can occur in most forms of leukemia, including chronic myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute myeloid leukemia, and prolymphocytic leukemia.[3]

Aleukemic leukemia cutis occurs when cancerous white blood cells penetrate the skin before they are detected in the bone marrow or peripheral circulation.[4]

  1. ^ a b James, William Daniel; Berger, Timothy G.; Elston, Dirk M. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. pp. 744–5. ISBN 978-0-7216-2921-6.
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1892. ISBN 978-1-4160-2999-1.
  3. ^ Leukemia Cutis at eMedicine
  4. ^ Du, Amy X; Hung, Tawny; Surmanowicz, Philip; Gniadecki, Robert (2020). "Diagnostic challenge of aleukemic leukemia cutis preceding acute myelogenous leukemia: A case report". SAGE Open Medical Case Reports. 8. SAGE Publications: 2050313X2091963. doi:10.1177/2050313x20919638. ISSN 2050-313X. PMC 7233898.