| Lexie Grey | |
|---|---|
| Grey's Anatomy character | |
 Chyler Leigh as Lexie Grey | |
| First appearance | As guest star: "Testing 1-2-3" (3.24) May 10, 2007 As series regular: "A Change Is Gonna Come" (4.01) September 27, 2007 |
| Last appearance | As series regular: "Flight" (8.24) May 17, 2012 As special guest star: "Breathe" (17.10) April 1, 2021 |
| Created by | Shonda Rhimes |
| Portrayed by | Chyler Leigh |
| In-universe information | |
| Full name | Alexandra Caroline Grey[1] |
| Nickname | Three, Lexipedia, Little Grey |
| Title | M.D. |
| Occupation | Surgical intern at Seattle Grace Hospital (seasons 4–5) Surgical resident at Seattle Grace Mercy West Hospital (seasons 6–8) |
| Family | Thatcher Grey (father; deceased) Susan Grey (mother; deceased) Molly Grey-Thompson (sister) Meredith Grey (half-sister) |
| Significant other | Mark Sloan (deceased)[2] Alex Karev Jackson Avery |
| Relatives | Eric Thompson (brother-in-law) Laura Grey-Thompson (niece) Derek Shepherd (brother-in-law; deceased) Zola Grey Shepherd (niece) Derek Bailey Shepherd (nephew) Ellis Shepherd (niece) |
| Nationality | American |
Alexandra Caroline Grey, M.D. is a character portrayed by Chyler Leigh on the ABC medical drama television series Grey's Anatomy created by Shonda Rhimes. She was first mentioned in season 2 before being introduced in season 3 as protagonist Meredith Grey's half-sister. Leigh was originally contracted to appear for a multi-episode story arc, but received star billing from seasons 4 through 8. She also reprised her role on the spin-off show Private Practice.
Characterized by Rhimes as a dork with issues expressing her feelings, Lexie transfers to the fictional Seattle Grace Hospital as a surgical intern after her mother's sudden death, eventually obtaining the position of surgical resident. Her focal storylines in the series included her struggles with the everyday life of being in a competitive profession, her initially strained relationship with Meredith, and her on-again, off-again romance with Mark Sloan. The couple sustained fatal injuries during an aviation accident in the season 8 finale, and Seattle Grace Mercy West is renamed Grey-Sloan Memorial Hospital in their memory.
Both the character and Leigh's performance have been positively received by critics and fans. Leigh was among the cast to receive a Screen Actors Guild Award nomination for Outstanding Performance by an Ensemble in a Drama Series in 2007.
- ^ "'Grey's Anatomy' boss Shonda Rhimes writes Mark Sloan obituary: 'I like to believe that Mark is with Lexie somewhere' -- EXCLUSIVE". Entertainment Weekly. Time Inc. October 4, 2012. Retrieved February 19, 2013.
- ^ "Mark Sloan (Eric Dane) Bio – Grey's Anatomy". ABC. Archived from the original on January 13, 2012. Retrieved June 6, 2018.