The Royal Library of Antioch was commissioned by Antiochus III (or Antiochus the Great) of the Seleucid Empire (a successor state of Alexander the Great's empire) around 221 B.C. in Antioch (now Antakya) and opened to scholars. Euphorion of Chalcis, an intellectually influential ancient poet from Greece, accepted the challenge issued by the king and established the royal library at Antioch. He also served as principal librarian until his death.[1]