Light-gated ion channel

Light-gated ion channels are a family of ion channels regulated by electromagnetic radiation. Other gating mechanisms for ion channels include voltage-gated ion channels, ligand-gated ion channels, mechanosensitive ion channels, and temperature-gated ion channels. Most light-gated ion channels have been synthesized in the laboratory for study, although two naturally occurring examples, channelrhodopsin and anion-conducting channelrhodopsin, are currently known.[1][2] Photoreceptor proteins, which act in a similar manner to light-gated ion channels, are generally classified instead as G protein-coupled receptors.

  1. ^ "Engineering Light-Gated Ion Channels"] — Biochemistry, 45 (51), 15129–15141, 2006 doi:10.1021/bi0618058
  2. ^ Govorunova, Elena G.; Sineshchekov, Oleg A.; Janz, Roger; Liu, Xiaoqin; Spudich, John L. (2015-08-07). "Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics". Science. 349 (6248): 647–650. Bibcode:2015Sci...349..647G. doi:10.1126/science.aaa7484. ISSN 0036-8075. PMC 4764398. PMID 26113638.