Liquefactive necrosis

Liquefactive necrosis (or colliquative necrosis) is a type of necrosis which results in a transformation of the tissue into a liquid viscous mass.[1] Often it is associated with focal bacterial or fungal infections, and can also manifest as one of the symptoms of an internal chemical burn.[2] In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes, resulting in a soft, circumscribed lesion consisting of pus and the fluid remains of necrotic tissue. Dead leukocytes will remain as a creamy yellow pus.[1] After the removal of cell debris by white blood cells, a fluid filled space is left. It is generally associated with abscess formation and is commonly found in the central nervous system.

  1. ^ a b Robbins and Cotran: Pathologic Basis of Disease, 8th Ed. 2010. Pg. 15
  2. ^ Ngan, Vanessa. "Chemical burn". DermNet New Zealand. Retrieved 4 February 2018.