The following is a list of the top National Football League (NFL) quarterbacks in regular season wins since quarterback starts were first officially tracked in 1950. In the NFL, the starting quarterback is the only position that is credited with records of wins and losses.
Tom Brady holds the record for the most regular season wins with 251. Brady also holds the record for the most postseason wins with 35.
Aaron Rodgers leads active players with 151 regular season wins. Patrick Mahomes leads active players with 15 postseason wins.
Otto Graham holds the record for the highest winning percentage with a minimum of 50 starts at .814 (57–13–1).