The following is a list of episodes of the situation comedy television series Samantha Who?. The program premiered on October 15, 2007 in the United States on the American Broadcasting Company (ABC).[2] Created by Don Todd and Cecelia Ahern, Samantha Who? follows the life of Samantha Newly (Christina Applegate) who was hit by a car and now has retrograde amnesia. Samantha Who? began its first season on October 15, 2007[2] and concluded on May 12, 2008.[3] A second season of the series aired on ABC's 2008–09 schedule from October 13, 2008 to July 23, 2009.[4] A total of 35 original episodes of Samantha Who? were produced over two seasons.
The show's first season was released to Region 1 DVD by ABC Studios and Disney Studios on September 23, 2008.[1] The second season was released to Region 1 DVD on August 25, 2009.[5]