| Ambassador of the United States to Panama | |
|---|---|
 Seal of the United States Department of State | |
 | |
| Nominator | The President of the United States |
| Appointer | The President with Senate advice and consent |
| Inaugural holder | William Insco Buchanan (as Envoy Extraordinary and Minister Plenipotentiary) |
| Formation | December 17, 1903 |
| Website | U.S. Embassy - Panama City |
The United States has maintained diplomatic relations with Panama since its separation from Colombia in 1903. The rank of the U.S. chief of mission to Panama was originally Envoy Extraordinary and Minister Plenipotentiary, but it was upgraded to Ambassador Extraordinary and Plenipotentiary in 1939.
Normal diplomatic relations between the United States and Panama have been interrupted only once, from January 10 to April 3, 1964, in the aftermath of the Martyrs' Day riots over sovereignty.