List of countries with their first Major League Baseball player

In 1964, Masanori Murakami became the first player born in Japan to appear in a major league game.

The following is a list of countries with their first Major League Baseball player. Listed are each country that at least one current or former major league player was born in, along with the name of the first person born in that country to play in a major league game, and the year and sports league of that player's major league debut.