Chemical & Engineering News publishes an annual list of the world's largest chemical producers by sales, excluding formulated products such as pharmaceutical drugs and coatings.[1] In 2018, sales of the top fifty companies amounted to US$951,000,000,000, an increase of 11.8% compared to the top fifty producers of 2017.[2] The American Chemistry Council estimated that global chemical sales in 2014 rose by 3.7% to US$5,389,000,000,000.[3]
In 2018, Forty-eight of the companies on the list disclosed chemical profits, which totaled US$110,100,000,000, an increase of 1.3% from 2017. The average profit margin for chemical operations for these companies was 9.6%.[1]