This is a list of Mesoamerican tlatoque of the altepetl of Tetzcoco from the first tlatoani in 1298 to the end of the line of indigenous rulers. From the early 15th century to 1521, Tetzcoco was one of the three leading members of the Triple Alliance, commonly known as the Aztec Empire, but was often subservient to the rulers of Tenochtitlan. The Aztec Empire was conquered by Spain in 1521, but the Spanish colonial authorities continued to appoint tlatoque of Tetzcoco until the office was abolished in 1564.