List of unsolved problems in chemistry

This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages) This article's factual accuracy is disputed. Relevant discussion may be found on the talk page. Please help to ensure that disputed statements are reliably sourced. (November 2011) (Learn how and when to remove this message) This article needs attention from an expert in chemistry. The specific problem is: Incomplete list. WikiProject Chemistry may be able to help recruit an expert. (November 2011) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "List of unsolved problems in chemistry" – news · newspapers · books · scholar · JSTOR (December 2014) (Learn how and when to remove this message) This article or section possibly contains synthesis of material which does not verifiably mention or relate to the main topic. Relevant discussion may be found on the talk page. (June 2021) (Learn how and when to remove this message) (Learn how and when to remove this message)

This is a list of unsolved problems in chemistry. Problems in chemistry are considered unsolved when an expert in the field considers it unsolved or when several experts in the field disagree about a solution to a problem.