Lobomycosis

Lobo's disease
Other namesLobo disease,[1] Jorge Lobo's disease,[2] Lacaziosis,[3] keloidal blastomycosis[4]
Histopathological changes in the skin seen in lobomycosis. Source: CDC
SpecialtyInfectious diseases Edit this on Wikidata
CausesLacazia loboi[1]

Lobomycosis is a fungal infection of the skin.[4] It usually presents with bumps in the skin, firm swellings, deep skin lesions, or malignant tumors.[1]

It is caused by Lacazia loboi (formerly named Loboa loboi).[5] Transmission is generally by direct contact with contaminated water, soil, vegetation, or by direct contact with an infected dolphin.[1]

Diagnosis is by identifying Lacazia laboi in a lesion.[1]

This disease is usually found in humans[6] and bottlenose dolphins, with the possible risk of transmission from one species to the other.[7]

It was discovered by Brazilian dermatologist Jorge Lobo. Other names which were given to the disease are: keloidal blastomycosis, Amazonian blastomycosis, blastomycoid granuloma, miraip and piraip. These last two names were given by natives of the Amazon and mean that which burns.[8]

  1. ^ a b c d e "ICD-11 - ICD-11 for Mortality and Morbidity Statistics". icd.who.int. Archived from the original on 1 August 2018. Retrieved 7 July 2021.
  2. ^ Talhari C, Oliveira CB, de Souza Santos MN, Ferreira LC, Talhari S (June 2008). "Disseminated lobomycosis". Int. J. Dermatol. 47 (6): 582–3. doi:10.1111/j.1365-4632.2008.03678.x. PMID 18477148. S2CID 205394764.
  3. ^ Xavier MB, Libonati RM, Unger D, et al. (February 2008). "Macrophage and TGF-beta immunohistochemical expression in Jorge Lobo's disease". Hum. Pathol. 39 (2): 269–74. doi:10.1016/j.humpath.2007.06.016. PMID 17959227.
  4. ^ a b Johnstone, Ronald B. (2017). "25. Mycoses and Algal infections". Weedon's Skin Pathology Essentials (2nd ed.). Elsevier. p. 464. ISBN 978-0-7020-6830-0. Archived from the original on 2023-01-10. Retrieved 2021-07-07.
  5. ^ Honda, Kord; Horner, Kyle (2006). "Lobomycosis". eMedicine. Archived from the original on 2022-02-12. Retrieved 2007-01-18.
  6. ^ Elsayed S, Kuhn SM, Barber D, Church DL, Adams S, Kasper R (April 2004). "Human case of lobomycosis". Emerging Infect. Dis. 10 (4): 715–8. doi:10.3201/eid1004.030416. PMC 3323076. PMID 15200867.
  7. ^ Reif, John S.; Schaefer, Adam M.; Bossart, Gregory D. (2013-10-01). "Lobomycosis: risk of zoonotic transmission from dolphins to humans". Vector Borne and Zoonotic Diseases. 13 (10): 689–693. doi:10.1089/vbz.2012.1280. ISSN 1557-7759. PMC 3787463. PMID 23919604.
  8. ^ Valdebran, Manuel (14 April 2017). "Lobomycosis: Background, Pathophysiology, Epidemiology". Medscape. WebMD. Archived from the original on 22 May 2023. Retrieved 17 September 2021.