Louis Bertrand may refer to:
- Louis Bertrand (saint) (1526–1581), Spanish Dominican priest
- Louis Bertrand (mathematician) (1731–1812), Swiss mathematician
- Louis Bertrand (Quebec seigneur) (1779–1871), Canadian politician and businessman
- Aloysius Bertrand (1807–1841), French poet
- Louis Bertrand (novelist) (1866–1941), French novelist, historian, and essayist
- Louis Bertrand (politician) (1856–1943), Belgian politician, author, and Minister of State