| Louise of Valois | |
|---|---|
 Possible portrait by Jean Clouet | |
| Born | 19 August 1515 Amboise, France |
| Died | 21 September 1518 (aged 3) |
| House | Valois-Angoulême |
| Father | Francis I of France |
| Mother | Claude of France |
Louise of Valois (c. 19 August 1515 – 21 September 1518), was the first child and first daughter of King Francis I of France and his first wife, Claude of France. She died in infancy, but was betrothed to Charles I of Spain for much of her life.