Lufkin may refer to:
- Lufkin, Texas, a city in Angelina County, Texas, United States
- Lufkin, Wisconsin, an unincorporated community, United States
- Lufkin Industries, manufacturing company based in Lufkin, Texas
- Lufkin (brand), a brand featuring primarily measurement tools
- Lufkin Foresters, former minor league baseball team based in Lufkin, Texas
- The Lufkin Daily News, newspaper that serves the city of Lufkin, Texas