MAPK13

MAPK13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3COI, 4EYJ, 4EYM, 4MYG, 4YNO, 5EKO, 5EKN
Identifiers
Aliases	MAPK13, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta, mitogen-activated protein kinase 13
External IDs	OMIM: 602899; MGI: 1346864; HomoloGene: 48133; GeneCards: MAPK13; OMA:MAPK13 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	36,144,524 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	28,999,207 bp
RNA expression pattern
	Top expressed in
	gums; ; mucosa of transverse colon; ; right adrenal gland; ; right adrenal cortex; ; gingival epithelium; ; left adrenal gland; ; mucosa of ileum; ; human penis; ; left adrenal cortex; ; parotid gland;
	Top expressed in
	granulocyte; ; lip; ; crypt of lieberkuhn of small intestine; ; epithelium of stomach; ; duodenum; ; large intestine; ; ileum; ; colon; ; intestinal villus; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; MAP kinase activity; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding;
Cellular component	cytosol; nucleus; cytoplasm;
Biological process	positive regulation of inflammatory response; regulation of transcription, DNA-templated; phosphorylation; transcription, DNA-templated; response to osmotic stress; protein phosphorylation; peptidyl-serine phosphorylation; positive regulation of interleukin-6 production; cell cycle; regulation of gene expression; cellular response to UV; stress-activated MAPK cascade; cellular response to hydrogen peroxide; cellular response to interleukin-1; cellular response to sorbitol; cellular response to anisomycin; cellular response to sodium arsenite; MAPK cascade; intracellular signal transduction; cellular response to organic substance;
	Sources:Amigo / QuickGO
Orthologs
	5603
	26415
	ENSG00000156711
	ENSMUSG00000004864
	O15264
	Q9Z1B7
	NM_002754
	NM_011950
	NP_002745
	NP_036080
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase 13 (MAPK 13), also known as stress-activated protein kinase 4 (SAPK4), is an enzyme that in humans is encoded by the MAPK13 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156711 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000004864 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: mitogen-activated protein kinase 13".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156711 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000004864 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: mitogen-activated protein kinase 13".

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