MCM7

MCM7
Identifiers
Aliases	MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104, minichromosome maintenance complex component 7
External IDs	OMIM: 600592; MGI: 1298398; HomoloGene: 4323; GeneCards: MCM7; OMA:MCM7 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	100,101,940 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	138,170,684 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; mucosa of transverse colon; ; lymph node; ; C1 segment; ; right testis; ; appendix; ; left testis; ; granulocyte; ; bone marrow;
	Top expressed in
	ventricular zone; ; epiblast; ; bone marrow; ; thymus; ; genital tubercle; ; tail of embryo; ; ganglionic eminence; ; embryo; ; embryo; ; yolk sac;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; helicase activity; DNA helicase activity; single-stranded DNA binding; protein binding; hydrolase activity; ATP binding; DNA binding; DNA replication origin binding; single-stranded 3'-5' DNA helicase activity;
Cellular component	membrane; nucleoplasm; chromatin; MCM complex; cytosol; nucleus; nucleolus;
Biological process	cellular response to organic substance; G1 phase; cellular response to xenobiotic stimulus; regulation of phosphorylation; cellular response to DNA damage stimulus; cellular response to epidermal growth factor stimulus; DNA replication initiation; cell cycle; cell population proliferation; DNA unwinding involved in DNA replication; DNA replication; G1/S transition of mitotic cell cycle; double-strand break repair via break-induced replication; pre-replicative complex assembly involved in nuclear cell cycle DNA replication; DNA strand elongation involved in DNA replication;
	Sources:Amigo / QuickGO
Orthologs
	4176
	17220
	ENSG00000166508
	ENSMUSG00000029730
	P33993
	Q61881
	NM_001278595; NM_005916; NM_182776
	NM_008568; NM_001356576; NM_001356577
	NP_001265524; NP_005907; NP_877577
	NP_032594; NP_001343505; NP_001343506
	Wikidata
View/Edit Human	View/Edit Mouse

DNA replication licensing factor MCM7 is a protein that in humans is encoded by the MCM7 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166508 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029730 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nakatsuru S, Sudo K, Nakamura Y (March 1995). "Isolation and mapping of a human gene (MCM2) encoding a product homologous to yeast proteins involved in DNA replication". Cytogenet Cell Genet. 68 (3–4): 226–30. doi:10.1159/000133918. PMID 7842741.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166508 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029730 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7842741-5] Nakatsuru S, Sudo K, Nakamura Y (March 1995). "Isolation and mapping of a human gene (MCM2) encoding a product homologous to yeast proteins involved in DNA replication". Cytogenet Cell Genet. 68 (3–4): 226–30. doi:10.1159/000133918. PMID 7842741.

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