MDMA-assisted psychotherapy is currently under investigation as a treatment for various other mental health disorders, including Major Depressive Disorder, social anxiety in autistic individuals, alcohol use disorder, and mood disturbances in individuals facing life-threatening illnesses.[6][7][8] The research is controversial[9][10] in part because recreational MDMA use has been associated with harmful effects among some users.[11][9][12]
^Bahji A, Forsyth A, Groll D, Hawken ER (January 2020). "Efficacy of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: A systematic review and meta-analysis". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 96: 109735. doi:10.1016/j.pnpbp.2019.109735. PMID31437480. S2CID201069918.
^Smith KW, Sicignano DJ, Hernandez AV, White CM (October 2021). "MDMA-Assisted Psychotherapy for Treatment of Posttraumatic Stress Disorder: A Systematic Review With Meta-Analysis". Journal of Clinical Pharmacology. 62 (4): 463–471. doi:10.1002/jcph.1995. PMID34708874. S2CID240072663.
^Illingworth BJ, Lewis DJ, Lambarth AT, Stocking K, Duffy JM, Jelen LA, Rucker JJ (May 2021). "A comparison of MDMA-assisted psychotherapy to non-assisted psychotherapy in treatment-resistant PTSD: A systematic review and meta-analysis". Journal of Psychopharmacology. 35 (5): 501–511. doi:10.1177/0269881120965915. PMID33345689. S2CID229341150.
^Pitts EG, Curry DW, Hampshire KN, Young MB, Howell LL (February 2018). "(±)-MDMA and its enantiomers: potential therapeutic advantages of R(-)-MDMA". Psychopharmacology. 235 (2): 377–392. doi:10.1007/s00213-017-4812-5. PMID29248945. S2CID3343930.
^Karlsen SN, Spigset O, Slørdal L (January 2008). "The dark side of ecstasy: neuropsychiatric symptoms after exposure to 3,4-methylenedioxymethamphetamine". Basic & Clinical Pharmacology & Toxicology. 102 (1): 15–24. doi:10.1111/j.1742-7843.2007.00159.x. PMID18047478.