MEROPS

MEROPS
Content
DescriptionMEROPS: the database of proteolytic enzymes, their substrates and inhibitors.
Contact
Research centerThe Wellcome Trust Sanger Institute
AuthorsNeil D Rawlings
Primary citationRawlings & al. (2012)[1]
Release date2010
Access
Websitehttps://www.ebi.ac.uk/merops/

MEROPS is an online database for peptidases (also known as proteases, proteinases and proteolytic enzymes) and their inhibitors.[2] The classification scheme for peptidases was published by Rawlings & Barrett in 1993,[3] and that for protein inhibitors by Rawlings et al. in 2004.[4] The most recent version, MEROPS 12.4, was released in late October 2021.[5]

  1. ^ Rawlings, Neil D; Barrett Alan J; Bateman Alex (January 2012). "MEROPS: the database of proteolytic enzymes, their substrates and inhibitors". Nucleic Acids Res. 40 (Database issue). England: D343-50. doi:10.1093/nar/gkr987. PMC 3245014. PMID 22086950.
  2. ^ Rawlings ND, Barrett AJ, Bateman A (January 2010). "MEROPS: the peptidase database". Nucleic Acids Res. 38 (Database issue): D227–33. doi:10.1093/nar/gkp971. PMC 2808883. PMID 19892822.
  3. ^ Rawlings, N.D. & Barrett, A.J. (1993) "Evolutionary families of peptidases." Biochem J 290, 205-218.
  4. ^ Rawlings, N.D., Tolle, D.P. & Barrett, A.J. (2004) "Evolutionary families of peptidase inhibitors." Biochem J 378, 705-716.
  5. ^ "What's New in MEROPS?".