MOPS

MOPS
Names
Preferred IUPAC name
3-(Morpholin-4-yl)propane-1-sulfonic acid
Other names
3-(N-Morpholino)propanesulfonic acid,
3-Morpholinopropanesulfonic acid,
3-N-Morpholino propansulfonic acid,
4-Morpholinepropanesulfonic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.013.162 Edit this at Wikidata
UNII
  • InChI=1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11) ☒N
    Key: DVLFYONBTKHTER-UHFFFAOYSA-N ☒N
  • InChI=1/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
    Key: DVLFYONBTKHTER-UHFFFAOYAN
  • C1COCCN1CCCS(=O)(=O)O
Properties
C7H15NO4S
Molar mass 209.26 g·mol−1
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H315, H319, H335
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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MOPS (3-(N-morpholino)propanesulfonic acid) is a buffer introduced in the 1960s, one of the twenty Good's buffers. It is a structural analog to MES,[1] and like MES, its structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.

  1. ^ Good, Norman E.; Winget, G. Douglas; Winter, Wilhelmina; Connolly, Thomas N.; Izawa, Seikichi; Singh, Raizada M. M. (1966). "Hydrogen Ion Buffers for Biological Research". Biochemistry. 5 (2): 467–77. doi:10.1021/bi00866a011. PMID 5942950.