MSRA (gene)

MSRA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2L90
Identifiers
Aliases	MSRA, PMSR, methionine sulfoxide reductase A
External IDs	OMIM: 601250; MGI: 106916; HomoloGene: 5812; GeneCards: MSRA; OMA:MSRA - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	10,428,891 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	64,693,352 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; cerebellar cortex; ; cerebellar hemisphere; ; human kidney; ; right hemisphere of cerebellum; ; bone marrow; ; apex of heart; ; bone marrow cells; ; blood; ; corpus callosum;
	Top expressed in
	right kidney; ; granulocyte; ; interventricular septum; ; human kidney; ; left lobe of liver; ; proximal tubule; ; right ventricle; ; duodenum; ; dentate gyrus of hippocampal formation granule cell; ; brown adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; peptide-methionine (S)-S-oxide reductase activity; L-methionine-(S)-S-oxide reductase activity;
Cellular component	extracellular exosome; nucleus; membrane; nucleoplasm; actin cytoskeleton; mitochondrion; cytoplasm; cytosol;
Biological process	methionine metabolic process; response to oxidative stress; protein repair; cellular response to oxidative stress;
	Sources:Amigo / QuickGO
Orthologs
	4482
	110265
	ENSG00000175806; ENSG00000285250
	ENSMUSG00000054733
	Q9UJ68
	Q9D6Y7
	NM_001135670; NM_001135671; NM_001199729; NM_012331
NM_001253712; NM_001253714; NM_001253715; NM_001253716; NM_026322;
	NM_001347639
	NP_001129142; NP_001129143; NP_001186658; NP_036463
NP_001240641; NP_001240643; NP_001240644; NP_001240645; NP_001334568;
	NP_080598
	Wikidata
View/Edit Human	View/Edit Mouse

Peptide methionine sulfoxide reductase (Msr) is a family of enzymes that in humans is encoded by the MSRA gene.^[5]^[6]

^ ^a ^b ^c ENSG00000285250 GRCh38: Ensembl release 89: ENSG00000175806, ENSG00000285250 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054733 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kuschel L, Hansel A, Schonherr R, Weissbach H, Brot N, Hoshi T, Heinemann SH (Sep 1999). "Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)". FEBS Lett. 456 (1): 17–21. doi:10.1016/S0014-5793(99)00917-5. PMID 10452521. S2CID 19104671.
^ "Entrez Gene: MSRA methionine sulfoxide reductase A".

[refGRCh38Ensembl-1] ENSG00000285250 GRCh38: Ensembl release 89: ENSG00000175806, ENSG00000285250 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054733 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10452521-5] Kuschel L, Hansel A, Schonherr R, Weissbach H, Brot N, Hoshi T, Heinemann SH (Sep 1999). "Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)". FEBS Lett. 456 (1): 17–21. doi:10.1016/S0014-5793(99)00917-5. PMID 10452521. S2CID 19104671.

[entrez-6] "Entrez Gene: MSRA methionine sulfoxide reductase A".

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