MYB (gene)

Myb-like DNA-binding domain
Identifiers
SymbolMyb_DNA-binding
PfamPF00249
InterProIPR001005
PROSITEPDOC00037
CATH1irz
SCOP21irz / SCOPe / SUPFAM
CDDcd00167
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
MYB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMYB, Cmyb, c-myb, c-myb_CDS, efg, MYB proto-oncogene, transcription factor
External IDsOMIM: 189990; MGI: 97249; HomoloGene: 31311; GeneCards: MYB; OMA:MYB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001198914
NM_010848
NM_033597

RefSeq (protein)

NP_001185843
NP_034978

Location (UCSC)Chr 6: 135.18 – 135.22 MbChr 10: 21 – 21.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myb genes are part of a large gene family of transcription factors found in animals and plants. In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper.[5][6] Members of the extended SANT/Myb family also include the SANT domain and other similar all-helical homeobox-like domains.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000118513Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019982Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chen Y, Xu H, Liu J, Zhang C, Leutz A, Mo X (Jul 2007). "The c-Myb functions as a downstream target of PDGF-mediated survival signal in vascular smooth muscle cells". Biochem Biophys Res Commun. 360 (2): 433–6. doi:10.1016/j.bbrc.2007.06.078. PMID 17599807.
  6. ^ "Entrez Gene: v-myb myeloblastosis viral oncogene homolog (avian)".