| Macrogryphosaurus Temporal range: Coniacian
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Scientific classification 
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| Domain: | Eukaryota |
| Kingdom: | Animalia |
| Phylum: | Chordata |
| Clade: | Dinosauria |
| Clade: | †Ornithischia |
| Clade: | †Neornithischia |
| Clade: | †Ornithopoda |
| Clade: | †Elasmaria |
| Genus: | †Macrogryphosaurus Calvo et al. 2007 |
| Species: | †M. gondwanicus
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| Binomial name | |
| †Macrogryphosaurus gondwanicus Calvo et al. 2007
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Macrogryphosaurus (meaning "big enigmatic lizard") is a genus of elasmarian dinosaur from the Coniacian age Upper Cretaceous Sierra Barrosa Formation (Neuquén Group) of Argentina in Patagonia. It was described by Jorge Calvo and colleagues in 2007, with M. gondwanicus as the type and only species.