Magnocellular red nucleus

Magnocellular red nucleus
Identifiers
NeuroLex IDbirnlex_720
Anatomical terms of neuroanatomy

The magnocellular red nucleus (mRN or mNR or RNm) is located in the rostral midbrain and is involved in motor coordination.[1][2] Together with the parvocellular red nucleus, the mRN makes up the red nucleus.[2] Due to the role it plays in motor coordination, the magnocellular red nucleus may be implicated in the characteristic symptom of restless legs syndrome (RLS).[3] The mRN receives most of its signals from the motor cortex and the cerebellum.[4][5]

  1. ^ Purves, Dale; Augustine, George C.; Fitzpatrick, David; Hall, William C.; LaMantia, Anthony-Samuel; White, Leonard E. (2012). Neuroscience (5th ed.). Sinauer Associates, Inc. pp. 269, 271–272. ISBN 978-0-87893-695-3.
  2. ^ a b Yamaguchi K, Goto N (August 2006). "Development of the human magnocellular red nucleus: a morphological study". Brain Dev. 28 (7): 431–5. doi:10.1016/j.braindev.2006.01.001. PMID 16516425. S2CID 8483275.
  3. ^ Baier, P. C.; Trenkwalder, CLAUDIA (2005-01-01), LeDoux, Mark (ed.), "CHAPTER N1 - Clinical Features and Animal Models of Restless Legs Syndrome and Periodic Limb Movement", Animal Models of Movement Disorders, Academic Press, pp. 755–758, doi:10.1016/b978-012088382-0/50067-0, ISBN 9780120883820, retrieved 2019-11-02
  4. ^ Gibson, A R; Houk, J C; Kohlerman, N J (January 1985). "Magnocellular red nucleus activity during different types of limb movement in the macaque monkey". The Journal of Physiology. 358: 527–549. doi:10.1113/jphysiol.1985.sp015565. ISSN 0022-3751. PMC 1193356. PMID 3981472.
  5. ^ Padel, Y. (1993). "[Magnocellular and parvocellular red nuclei. Anatomico-functional aspects and relations with the cerebellum and other nerve centres]". Revue Neurologique. 149 (11): 703–715. ISSN 0035-3787. PMID 8091083.