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3D model (JSmol)
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PubChem CID
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Properties | |
C56H88N12O20[1] | |
Molar mass | 1249.384 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Malacidins are a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria. Their activity appears to be dependent on calcium. The discovery of malacidins was published in 2018.[2]
The malacidin family were discovered using a new method of soil microbiome screening that does not require cell culturing.[3] This allowed researchers to identify genetic components necessary to produce the chemical. Malacidin A was shown to kill Staphylococcus aureus and other Gram-positive bacteria.
At the time of publication it was not certain if the discovery would lead to any new antibiotic drugs, because large investments of time and money are required to determine whether any drug is safe and effective.[4]
wapost
was invoked but never defined (see the help page).