Mamia I Gurieli (Georgian: მამია I გურიელი; died 1534), of the House of Gurieli, was Prince of Guria from 1512 until his death in 1534. Succeeding on the death of his father Giorgi I Gurieli, Mamia became involved in the conflict between the two eastern Georgian kingdoms of Kartli and Kakheti in 1520; by force of arms, he compelled David X of Kartli to agree on peace with Levan of Kakheti, his son-in-law. Mamia Gurieli's 1533 campaign, jointly with his namesake Prince of Mingrelia, against the homebase of Circassian pirates ended in a fiasco, with Mamia being captured and ransomed later that year.