Man a Machine (French: L'homme machine) is a work of materialist philosophy by the 18th-century French physician and philosopher Julien Offray de La Mettrie, first published in 1747.[1] In this work, de La Mettrie extends Descartes' argument that animals are mere automatons, or machines, to human beings. He denies dualism and the existence of the soul as a substance separate from matter.