A manticore is a mythical creature similar to a chimera.
Manticore can also refer to:
- Manticore Records, a music label
- Manticore (Boogiepop), a character from Boogiepop and Others
- Manticore (2005 film), a Sci Fi Pictures original film
- Manticore (2022 film), a Spanish film
- Manticore, a fictional secret governmental organization in the television series Dark Angel
- Manticore, a fictional secret organization in the television series Citadel
- Manticore, a character who is part of the Onslaught team in the DC Comics universe
- Manticore, a character from the comic based on the video game City of Heroes
- "Manticore", a song by Ninja Sex Party from their 2011 album NSFW
- Manticore, a bio-weapon developed by Atlas Corporation in the video game Call of Duty: Advanced Warfare
- The Manticore, a novel by Robertson Davies
- "The Manticore", a song by Scottish musician Momus from his 2015 album Glyptothek
- Tiny Manticore, a character from Adventure Time episode "Normal Man"