| Manuel III Megas Komnenos | |
|---|---|
| Emperor and Autocrat of all the East and Perateia | |
 Coin of Manuel III, depicting him on horseback | |
| Emperor of Trebizond | |
| Reign | 20 March 1390 – 5 March 1417 |
| Predecessor | Alexios III |
| Successor | Alexios IV |
| Born | 16 December 1364 |
| Died | 5 March 1417 (aged 52) |
| Spouse | Eudokia of Georgia Anna Philanthropene |
| Issue | Alexios IV Megas Komnenos |
| Dynasty | Komnenos |
| Father | Alexios III Megas Komnenos |
| Mother | Theodora Kantakouzene |
Manuel III Megas Komnenos (Greek: Μανουήλ Μέγας Κομνηνός; 16 December 1364 – 5 March 1417)[1] was Emperor of Trebizond from 20 March, 1390 to his death in 1417.
The major event of Manuel's reign was the arrival of the Central Asian conqueror Tamerlane to Anatolia. This led to the virtual destruction of the Ottoman Empire, which had threatened the existence of Manuel's domain, in the Battle of Ankara. Although the Ottomans reconstituted their state after 10 years of civil war, this defeat extended the life and security of the Empire of Trebizond for several more decades.
- ^ Vougiouklaki Penelope, "Manuel III Grand Komnenos", Encyclopedia of the Hellenic World: Asia Minor