Manuel Quintero Villareal | |
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| Born | November 17, 1860 Pesé, Panama, Granadine Confederation |
| Died | February 22, 1954 (aged 93) Panama City, Panamá Province, Panama |
| Allegiance |  Panama |
| Branch | Panamanian Defense Forces |
| Years of service | c. 1899 – ??? |
| Rank |  General de Ejército |
| Battles/wars | Thousand Days' War Coto War |
Manuel de los Dolores Quintero Villarreal was a Panamanian general and politician during the early 20th-century. He was known for being one of the main figures during the Coto War as well as a participant in the Thousand Days' War. He was also the Porrista Liberal Party nominee of the 1924 Panamanian general election.