Margaret Beaufort (1443–1509), Countess of Richmond and Derby, was a leading figure in the Wars of the Roses and the mother of King Henry VII of England.
Other people called Margaret Beaufort include:
- Margaret Beaufort, Countess of Devon (c. 1409–1449), daughter of John Beaufort, 1st Earl of Somerset; mother of Thomas Courtenay, 14th Earl of Devon, and John Courtenay, 15th Earl of Devon
- Margaret Beaufort, Countess of Stafford (c. 1437–1474), daughter of Edmund Beaufort, 2nd Duke of Somerset; mother of Henry Stafford, 2nd Duke of Buckingham