| Maria Caterina Farnese | |||||
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| Duchess consort of Modena and Reggio | |||||
| Tenure | 11 January 1631 – 25 July 1646 | ||||
| Born | 18 February 1615 Parma, Duchy of Parma and Piacenza | ||||
| Died | 25 July 1646 (aged 31) Ducal Palace of Sassuolo, Modena, Duchy of Modena | ||||
| Spouse | Francesco I d'Este, Duke of Modena | ||||
| Issue Detail | Alfonso IV, Duke of Modena Isabella, Duchess of Parma Eleonora d'Este Maria, Duchess of Parma | ||||
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| House | Farnese | ||||
| Father | Ranuccio I Farnese, Duke of Parma | ||||
| Mother | Margherita Aldobrandini | ||||
Maria Caterina Farnese (18 February 1615 – 25 July 1646) was a member of the Ducal House of Farnese. She was Duchess of Modena as the first wife of Francesco I d'Este, Duke of Modena. In some sources she is known simply as Maria Farnese.