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| Maria Cristina | |
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| Born | 24 August 1609 Florence Grand Duchy of Tuscany |
| Died | 9 August 1632 (aged 22) Villa del Poggio Imperiale Arcetri, Florence Grand Duchy of Tuscany |
| House | Medici |
| Father | Cosimo II de' Medici, Grand Duke of Tuscany |
| Mother | Archduchess Maria Maddalena of Austria |
Maria Cristina de 'Medici (24 August 1609 – 9 August 1632) was a Tuscan princess and the first born child of Cosimo II de' Medici, Grand Duke of Tuscany.