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Maria Mikhaĭlovna Manàsseina, also known as Marie de Manacéïne, was born in Korkunova in 1841 and died in Saint Petersburg on 17 March in 1903. She was buried at the Novodévitxi cemetery. Manàsseina was the daughter of Mikhaïl Korkunov, a historian; her brother Nikolai Korkunov was a philosopher. She was the disciple of the professor Ivan Tarkhànov.
Manàsseina was one of the first women in the Russian Empire to graduate in medicine. First, she received a special certification authorizing her as a "female doctor" and, later, the official Medicine degree certification. She is nowadays considered an expert neuroscientist in the field of physiological chemistry and a pioneer in somnology (the study of sleep or sleep science) and biochemistry. She published numerous articles in French, Russian, and German under different names: Marie de Manacéïne, Maria Manàsseina, or Marie von Manassein. She was not uncommonly referred to as a male doctor. Despite her outstanding contributions, in the last ten years,[may be outdated as of March 2023] her name has not been cited more than 100 times.