Mary Wilson may refer to:
- Mary Wilson, Baroness Wilson of Rievaulx (1916–2018), British poet, wife of Harold Wilson
- Mary L. G. Carus-Wilson (1861–1935), English author and speaker
- Mary Louise Wilson (born 1931), American film, musical theatre, stage and television actress
- Mary Wilson (singer) (1944–2021), American singer, member of Motown group The Supremes
- Mary Wilson, host of Radio New Zealand's Checkpoint news programme
- Mary Ellen Wilson (1864–1956), child abuse victim whose case spurred on the founding of the New York Society for the Prevention of Cruelty to Children
- Mary Wilson (broadcaster), Irish broadcaster and journalist
- Mary Elizabeth Wilson (1893–1963), serial killer known as "the Merry widow of Windy Nook"
- Mary Evans Wilson (1866–1928), Boston civil rights activist
- Mary Ann Wilson (born 1936), American nurse and TV exercise presenter
- Mary Anne Wilson (1802–1867), English opera singer
- Mary Wilson, character in Angels with Broken Wings
- Mary Wilson, widow of Ralph Wilson and leader of the trust that holds ownership of the Buffalo Bills
- Mary Pat Wilson (born 1963), Puerto Rican Olympic skier
- Mary Wilson (politician), Canadian politician
- Mary Florence Wilson (1884–1977), librarian for the League of Nations
- Mary Jane Wilson (1840–1916), founded the Catholic religious order, the Congregation of the Franciscan Sisters of Our Lady of Victories
- Mary Georgina Wade Wilson (1856–1939), Scottish artist
- Mary J. Wilson (1937–2020), African-American zookeeper
- Mary Wilson (figure skater) (born 1940), Australian figure skater
- Mary Louise Defender Wilson (born 1930), Native American storyteller, scholar and educator
- Mary Dunstan Wilson (1870–1959), Australian educator and nun
- Mary Street Wilson, American pastor, teacher, math professor, social justice activist, and candidate in the 2018 United States House of Representatives elections in Texas