British chemist (born 1973)
Matthew Houghton Todd (born 13 January 1973) is a British chemist and the Professor and Chair of Drug Discovery of the School of Pharmacy at University College London .[ 1] He is the founder of Open Source Malaria (OSM) and his research focuses on drug discovery and development for this disease.[ 2] [ 3] [ 4] [ 5] [ 6] Recently, he has expanded to other areas, particularly neglected diseases such as tuberculosis and mycetoma [ 7] in the Open Source Tuberculosis (OSTB) and Open Source Mycetoma (MycetOS) project, through a collaboration with the Drugs for Neglected Diseases Initiative and Erasmus MC .[ 8] In addition, he has some research activity in catalysis and methodology .[ 9] [ 10] [ 11] [ 12]
^ "Professor Matthew Todd – UCL School of Pharmacy" . 2 October 2018.
^ Peplow, M (2019). "Open-source drug discovery takes aim at malaria and neglected diseases" . C&EN . ACS. Retrieved 13 February 2019 .
^ Lowe, D. "The Open Source Malaria Project, So Far" . In The Pipeline . Retrieved 13 February 2019 .
^ Williamson, AE (2016). "Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles" . ACS Central Science . 2 (10): 687–701. doi :10.1021/acscentsci.6b00086 . PMC 5084075 . PMID 27800551 .
^ Robertson, MN (2014). "Open source drug discovery – A limited tutorial" . Parasitology . 141 (1): 148–157. doi :10.1017/S0031182013001121 . PMC 3884843 . PMID 23985301 .
^ Tse, EG; Korsik, M; Todd, MH (2019). "The past, present and future of anti-malarial medicines" . Malaria Journal . 18 (1): 93. doi :10.1186/s12936-019-2724-z . PMC 6431062 . PMID 30902052 .
^ Lim, W (2018). "Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma" . PLOS Neglected Tropical Diseases . 12 (2): e0006437. doi :10.1371/journal.pntd.0006437 . PMC 5940239 . PMID 29698504 .
^ "MycetOS – DNDi" . 31 December 2017.
^ Park, SJ (2002). "Oxidative Arylation of Isochroman" . Journal of Organic Chemistry . 77 (2): 949–955. doi :10.1021/jo2021373 . PMID 22142205 .
^ Tsang, ASK (2009). "Facile synthesis of vicinal diamines via oxidation of N-phenyltetrahydroisoquinolines with DDQ". Tetrahedron Letters . 50 (11): 1199–1202. doi :10.1016/j.tetlet.2008.12.101 .
^ Hashmi, ASK (2010). "Gold-Catalysis: Reactions of Organogold Compounds with Electrophiles". Australian Journal of Chemistry . 63 (12): 1619–1626. doi :10.1071/CH10342 .
^ Ahamed, M (2010). "Catalytic Asymmetric Additions of Carbon-Centered Nucleophiles to Nitrogen-Containing Aromatic Heterocycles". European Journal of Organic Chemistry . 2010 (31): 5935–5942. doi :10.1002/ejoc.201000877 .