Mature T-cell lymphoma, also called peripheral T-cell lymphoma, is a group of rare, aggressive lymphomas that develop from mature white blood cells and originate from lymphoid tissues outside of the bone marrow. Mature T-cell lymphoma is under the category of non-Hodgkin lymphoma. Mature T-cell lymphomas account for 10% to 15% of all lymphomas and is more common in Asia than in Europe and America.[1] Its common subtypes include angioimmunoblastic T-cell lymphoma, anaplastic large cell lymphoma and peripheral T-cell lymphoma not otherwise specified.[1] While different subtypes have variable symptoms, common symptoms include enlarged painless lymph nodes, fever, weight loss, rash and night sweats.[2]
Some subtypes of mature T-cell lymphoma may be associated with viral exposure[3][4] as well as gene mutations.[5] Diagnosis is done by physical examinations, assisted by tests like biopsy, PET scan and CT scan to examine the site of lymph node development.[6] Chemotherapy, drugs, autologous stem cell treatment and extracorporeal photopheresis are treatment options.[7] The choice of treatment and its subsequent effectiveness are determined by the subtype present in the patient.
- ^ a b Swerdlow, Steven H., Herausgeber. (18 September 2017). WHO classification of tumours of haematopoietic and lymphoid tissues. International Agency for Research on Cancer. ISBN 978-92-832-4494-3. OCLC 1004779841.
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:8was invoked but never defined (see the help page). - ^ "Lymphoma Action | Tests, diagnosis and staging". Lymphoma Action. Retrieved 2020-04-26.
- ^ "Peripheral T-Cell Lymphoma: Treatment Options - LRF". Lymphoma Research Foundation. Retrieved 2020-04-26.