Mead acid

Mead acid
Names
Preferred IUPAC name
(5Z,8Z,11Z)-Icosa-5,8,11-trienoic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
  • InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h9-10,12-13,15-16H,2-8,11,14,17-19H2,1H3,(H,21,22)/b10-9-,13-12-,16-15- ☒N
    Key: UNSRRHDPHVZAHH-YOILPLPUSA-N ☒N
  • InChI=1/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h9-10,12-13,15-16H,2-8,11,14,17-19H2,1H3,(H,21,22)/b10-9-,13-12-,16-15-
    Key: UNSRRHDPHVZAHH-YOILPLPUBD
  • CCCCCCCC\C=C/C\C=C/C\C=C/CCCC(=O)O
Properties
C20H34O2
Molar mass 306.48276
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Mead acid is an omega-9 fatty acid, first characterized by James F. Mead.[1] As with some other omega-9 polyunsaturated fatty acids, animals can make Mead acid de novo. Its elevated presence in the blood is an indication of essential fatty acid deficiency.[2] Mead acid is found in large quantities in cartilage.

  1. ^ Siegel, George J.; Albers, R. Wayne (2006). Basic neurochemistry: molecular, cellular, and medical aspects, Volume 1 (7th ed.). Elsevier. p. 40. ISBN 9780080472072. One of these is 20:3ω9, termed 'Mead acid' after its discovery by James Mead....
  2. ^ Ichi I; Kono N; Arita Y; Haga S (January 2014). "Identification of genes and pathways involved in the synthesis of Mead acid (20:3n−9), an indicator of essential fatty acid deficiency". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1841 (1): 204–213. doi:10.1016/j.bbalip.2013.10.013. PMID 24184513.