The mean corpuscular hemoglobin concentration (MCHC) is a measure of the concentration of hemoglobin in a given volume of packed red blood cell.
It is calculated by dividing the hemoglobin by the hematocrit. Reference ranges for blood tests are 32 to 36 g/dL (320 to 360g/L),[1] or between 4.81 and 5.58 mmol/L. It is thus a mass or molar concentration. Still, many instances measure MCHC in percentage (%), as if it were a mass fraction (mHb / mRBC).[2][3] Numerically, however, the MCHC in g/dL and the mass fraction of hemoglobin in red blood cells in % are identical, assuming an RBC density of 1g/mL and negligible hemoglobin in plasma.[citation needed]