Medical missions in China by Catholic and Protestant physicians and surgeons of the 19th and early 20th centuries laid many foundations for modern medicine in China. Western medical missionaries established the first modern clinics and hospitals, provided the first training for nurses, and opened the first medical schools in China.[1] Work was also done in opposition to the abuse of opium. Medical treatment and care came to many Chinese who were addicted, and eventually public and official opinion was influenced in favor of bringing an end to the destructive trade.[2] By 1901, China was the most popular destination for medical missionaries. The 150 foreign physicians operated 128 hospitals and 245 dispensaries, treating 1.7 million patients. In 1894, male medical missionaries comprised 14 percent of all missionaries; women doctors were four percent. Modern medical education in China started in the early 20th century at hospitals run by international missionaries.[3]