Melatonin receptor 1A

MTNR1A
Identifiers
Aliases	MTNR1A, MEL-1A-R, MT1, Melatonin receptor 1A
External IDs	OMIM: 600665; MGI: 102967; HomoloGene: 21207; GeneCards: MTNR1A; OMA:MTNR1A - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	186,555,567 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	45,541,543 bp
RNA expression pattern
	Top expressed in
	testicle; ; palpebral conjunctiva; ; rectum; ; islet of Langerhans; ; human kidney; ; appendix; ; gallbladder; ; cerebellar cortex; ; cerebellar hemisphere; ; mucosa of transverse colon;
	Top expressed in
	lens; ; embryo; ; embryo; ; epithelium of lens; ; suprachiasmatic nucleus; ; spermatid; ; superior cervical ganglion; ; liver; ; left lobe of liver; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hormone binding; G protein-coupled receptor activity; organic cyclic compound binding; signal transducer activity; protein binding; melatonin receptor activity;
Cellular component	integral component of membrane; membrane; receptor complex; integral component of plasma membrane; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; mating behavior; signal transduction; circadian rhythm; G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	4543
	17773
	ENSG00000168412
	ENSMUSG00000054764
	P48039
	Q61184
	NM_005958
	NM_008639
	NP_005949
	NP_032665
	Wikidata
View/Edit Human	View/Edit Mouse

Melatonin receptor type 1A is a protein that in humans is encoded by the MTNR1A gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168412 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054764 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Slaugenhaupt SA, Roca AL, Liebert CB, Altherr MR, Gusella JF, Reppert SM (May 1995). "Mapping of the gene for the Mel1a-melatonin receptor to human chromosome 4 (MTNR1A) and mouse chromosome 8 (Mtnr1a)". Genomics. 27 (2): 355–7. doi:10.1006/geno.1995.1056. PMID 7558006.
^ "Entrez Gene: MTNR1A melatonin receptor 1A".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168412 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054764 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7558006-5] Slaugenhaupt SA, Roca AL, Liebert CB, Altherr MR, Gusella JF, Reppert SM (May 1995). "Mapping of the gene for the Mel1a-melatonin receptor to human chromosome 4 (MTNR1A) and mouse chromosome 8 (Mtnr1a)". Genomics. 27 (2): 355–7. doi:10.1006/geno.1995.1056. PMID 7558006.

[entrez-6] "Entrez Gene: MTNR1A melatonin receptor 1A".

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