Menthorpe is a hamlet in the civil parish of North Duffield in North Yorkshire, England. It lies on the west bank of the River Derwent, 6 miles (10 km) east of Selby.
Menthorpe Ings, north of the hamlet, is a flood meadow which is part of the Derwent Ings Site of Special Scientific Interest, internationally important for its concentration of water-fowl in winter.