Mepartricin

Mepartricin
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (19E,21E,23Z,25Z,27E,29E,31E)-Methyl 34-((2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-1,3,5,7,9,13,37-heptahydroxy-17-(5-hydroxy-7-[4-(methylamino)phenyl]-7-oxoheptan-2-yl)-18-methyl-11,15-dioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.057.786 Edit this at Wikidata
Chemical and physical data
FormulaC60H88N2O19
Molar mass1141.359 g·mol−1
3D model (JSmol)
  • CNc1ccc(cc1)C(=O)CC(O)CCC(C)C3OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC4(O)CC(O)C(C(=O)OC)C(CC(O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)/C=C/C=C/C=C/C=C\C=C/C=C/C=C/C3C)O4
  • InChI=1S/C60H88N2O19/c1-36-18-16-14-12-10-8-6-7-9-11-13-15-17-19-48(79-59-56(74)54(61)55(73)38(3)78-59)33-51-53(58(75)77-5)50(71)35-60(76,81-51)34-47(69)30-45(67)28-43(65)26-42(64)27-44(66)29-46(68)32-52(72)80-57(36)37(2)20-25-41(63)31-49(70)39-21-23-40(62-4)24-22-39/h6-19,21-24,36-38,41-43,45-48,50-51,53-57,59,62-65,67-69,71,73-74,76H,20,25-35,61H2,1-5H3/b7-6-,10-8-,11-9+,14-12+,15-13+,18-16+,19-17+/t36?,37?,38-,41?,42?,43?,45?,46?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59+,60?/m1/s1 checkY
  • Key:GVEVTKSEPQUIJA-PLDHRHJXSA-N checkY
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Mepartricin is a macrolide polyene compound that is useful for urethra, prostate, and bladder function. It has been studied for use in treating chronic pelvic pain syndrome and benign prostatic hyperplasia.[1][2]

  1. ^ De Rose AF, Gallo F, Giglio M, Carmignani G (January 2004). "Role of mepartricin in category III chronic nonbacterial prostatitis/chronic pelvic pain syndrome: a randomized prospective placebo-controlled trial". Urology. 63 (1): 13–6. doi:10.1016/j.urology.2003.08.006. PMID 14751338.
  2. ^ Erickson BA, Schaeffer AJ, Van Le B (2008). "Chronic prostatitis". Clin Evid (Online). 2008. PMC 2907954. PMID 19450305.