 | This article needs attention from an expert in medicine. The specific problem is: Unsure about recent edits. (December 2020) |
| Merkel cell carcinoma | |
|---|---|
 | |
| Micrograph of a Merkel cell carcinoma. H&E stain. | |
| Specialty | Oncology |
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about three people per million members of the population.[1] It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin.[2] Factors involved in the development of MCC include the Merkel cell polyomavirus (MCPyV or MCV), a weakened immune system, and exposure to ultraviolet radiation.[3] Merkel cell carcinoma usually arises on the head, neck, and extremities, as well as in the perianal region and on the eyelid.[4] It is more common in people over sixty years old, Caucasian people, and males.[5] MCC is less common in children.[1][4]
- ^ a b "Merkel cell carcinoma". Dynamed. Retrieved 2019-11-11.
- ^ Dermatology. Bolognia, Jean., Jorizzo, Joseph L., Rapini, Ronald P. (2nd ed.). St. Louis, MO: Mosby/Elsevier. 2008. ISBN 978-1-4160-2999-1. OCLC 212399895.
{{cite book}}: CS1 maint: others (link)[page needed] - ^ Kervarrec, Thibault; Samimi, Mahtab; Guyétant, Serge; Sarma, Bhavishya; Chéret, Jérémy; Blanchard, Emmanuelle; Berthon, Patricia; Schrama, David; Houben, Roland; Touzé, Antoine (10 June 2019). "Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review". Frontiers in Oncology. 9: 451. doi:10.3389/fonc.2019.00451. PMC 6579919. PMID 31245285.
- ^ a b Patterson, James W. (James Willis), 1946- (2014-12-07). Weedon's skin pathology. Hosler, Gregory A. (Fourth ed.). [Edinburgh?]. ISBN 978-0-7020-6200-1. OCLC 900724639.
{{cite book}}: CS1 maint: location missing publisher (link) CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link) - ^ Pulitzer, Melissa (June 2017). "Merkel Cell Carcinoma". Surgical Pathology Clinics. 10 (2): 399–408. doi:10.1016/j.path.2017.01.013. PMC 5443625. PMID 28477888.