Mesoporous silica is a form of silica that is characterised by its mesoporous structure, that is, having pores that range from 2 nm to 50 nm in diameter. According to IUPAC's terminology, mesoporosity sits between microporous (<2 nm) and macroporous (>50 nm). Mesoporous silica is a relatively recent development in nanotechnology. The most common types of mesoporous nanoparticles are MCM-41 and SBA-15.[2] Research continues on the particles, which have applications in catalysis, drug delivery and imaging.[3] Mesoporous ordered silica films have been also obtained with different pore topologies.[4]
A compound producing mesoporous silica was patented around 1970.[5][6][7] It went almost unnoticed[8] and was reproduced in 1997.[9] Mesoporous silica nanoparticles (MSNs) were independently synthesized in 1990 by researchers in Japan.[10] They were later produced also at Mobil Corporation laboratories[11] and named Mobil Composition of Matter (or Mobil Crystalline Materials, MCM).[12]
Six years later, silica nanoparticles with much larger (4.6 to 30 nanometer) pores were produced at the University of California, Santa Barbara.[13] The material was named Santa Barbara Amorphous type material, or SBA-15. These particles also have a hexagonal array of pores.
The researchers who invented these types of particles planned to use them as molecular sieves. Today, mesoporous silica nanoparticles have many applications in medicine, biosensors,[14] thermal energy storage,[15] water/gas filtration [16] and imaging.
^Cite error: The named reference A.B.D. Nandiyanto; S.-G Kim; F. Iskandar; and K. Okuyama 2009 447–453 was invoked but never defined (see the help page).
^Katiyar, Amit; Yadav, Santosh; Smirniotis, Panagiotis G.; Pinto, Neville G. (July 2006). "Synthesis of ordered large pore SBA-15 spherical particles for adsorption of biomolecules". Journal of Chromatography A. 1122 (1–2): 13–20. doi:10.1016/j.chroma.2006.04.055. ISSN0021-9673. PMID16716334.
^Trewyn, Brian G; Nieweg, Jennifer A; Zhao, Yannan; Lin, Victor S.-Y. (2007). "Biocompatible mesoporous silica nanoparticles with different morphologies for animal cell membrane penetration". Chemical Engineering Journal. 137 (1): 23–29. doi:10.1016/j.cej.2007.09.045.
^Chiola, V.; Ritsko, J. E. and Vanderpool, C. D. "Process for producing low-bulk density silica." Application No. US 3556725D A filed on 26-Feb-1969; Publication No. US 3556725 A published on 19-Jan-1971
^Beck, J. S.; Vartuli, J. C.; Roth, W. J.; Leonowicz, M. E.; Kresge, C. T.; Schmitt, K. D.; Chu, C. T. W.; Olson, D. H.; Sheppard, E. W. (1992). "A New Family of Mesoporous Molecular Sieves Prepared with Liquid Crystal Templates". Journal of the American Chemical Society. 114 (27): 10834–10843. doi:10.1021/ja00053a020.
^Valenti G, Rampazzo R, Bonacchi S, Petrizza L, Marcaccio M, Montalti M, Prodi L, Paolucci F (2016). "Variable Doping Induces Mechanism Swapping in Electrogenerated Chemiluminescence of Ru(bpy)32+ Core−Shell Silica Nanoparticles". J. Am. Chem. Soc. 138 (49): 15935–15942. doi:10.1021/jacs.6b08239. hdl:11585/583548. PMID27960352.
^Mitran, Raul−Augustin; Berger, Daniela; Munteanu, Cornel; Matei, Cristian (2015). "Evaluation of Different Mesoporous Silica Supports for Energy Storage in Shape-Stabilized Phase Change Materials with Dual Thermal Responses". The Journal of Physical Chemistry C. 119 (27): 15177–15184. doi:10.1021/acs.jpcc.5b02608.