Metabotropic glutamate receptor

Metabotropic glutamate receptor dimer (Type 2) in ribbon representation
L-Glutamic acid

The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs.[1] Like all glutamate receptors, mGluRs bind with glutamate, an amino acid that functions as an excitatory neurotransmitter.

  1. ^ Bonsi P, Cuomo D, De Persis C, Centonze D, Bernardi G, Calabresi P, Pisani A (2005). "Modulatory action of metabotropic glutamate receptor (mGluR) 5 on mGluR1 function in striatal cholinergic interneurons". Neuropharmacology. 49. 49 (Suppl 1): 104–13. doi:10.1016/j.neuropharm.2005.05.012. PMID 16005029. S2CID 25980146.