Metallothionein-3 (also known as Growth Inhibitory Factor) is a protein that in humans is encoded by the MT3gene.[5][6][7]
It is a 68-amino acid peptide (20 of which are cysteine) that is abnormally under-expressed in the brains of patients with Alzheimer's disease.[8]
Metallothionein-3 is a member of the metallothionein family of proteins.
^Felizola SJ, Nakamura Y, Arata Y, Ise K, Satoh F, Rainey WE, Midorikawa S, Suzuki S, Sasano H (Sep 2014). "Metallothionein-3 (MT-3) in the human adrenal cortex and its disorders". Endocrine Pathology. 25 (3): 229–235. doi:10.1007/s12022-013-9280-9. PMID24242700. S2CID39871076.
^Uchida, Y; Takio, K; Titani, K; Ihara, Y; Tomonaga, M (August 1991). "The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein". Neuron. 7 (2): 337–347. doi:10.1016/0896-6273(91)90272-2. PMID1873033. S2CID25819090.